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See full list on verywellhealth.com what is symax duotab Motrin Ibuprofen Pain Reliever and Fever Reducer, 50 Caplets Ibuprofen Tablets USP (200 mg per Caplet) Pain Reliever, Fever Reducer (NSAID) 50 Packets Official answer. by Drugs.com. There is no real difference. Motrin and Advil are both brands of ibuprofen and are equally effective. Motrin, Motrin IB and Advil are brand names for the drug ibuprofen. Ibuprofen belongs to a group of medicines called NSAIDs.